Primary Objective
The Nash Laboratory studies how key players of neuronal function, such as glutamate receptors, synaptic and motor proteins, and mitochondrial proteins, regulate brain function in healthy and diseased states. We combine the most clinically and physiologically relevant behavioural, imaging and electrophysiological techniques, to tease apart the molecular processes regulating neurotransmission, synaptic plasticity, homeostasis, and cellular metabolism.
Current Research
Understanding the role of transmembrane receptors and synaptic proteins in controlling neurotransmission and synaptic plasticity in the basal ganglia in health and disease.The role of mitochondria in neurodegenerative diseases.Decoding the pathological mechanisms underpinning Parkinson’s disease.Novel treatment strategies for diseases, disorders and syndromes of the CNS.
Goals of Research
We tease apart the neurobiological mechanisms regulating human behaviour. Our goal is to improve the lives of people with disorders of the CNS.
